Endocrine Abstracts

Recent guidelines on diabetes treatment provide that bariatric surgery should be the most logical & cost-effective means of controlling Type 2 diabetes.Objectives: To compare laparoscopic mini-gastric bypass vs laparoscopic sleeve gastrectomy regarding the efficacy of control of D.M in obese patients.Summary: A randomized controlled study conducted on 60 obese patients with type 2 D.M divided into, group (1): 30 patients treate...

Introduction: T1DM is caused by immune mediated destruction of pancreatic β-cells, leading to partial, or absolute insulin deficiency.The most frequent age of onset is 12 years. IGF-1 is a polypeptide with 70 amino acids and its chemical structure is similar to insulin. IGF-1 is associated with early development and has anabolic effect in adults. IGF-1 regulates many physiological functions, including glucose metabolism, cell survival and proliferation.<p class="abste...

Background: Worsening hyperglycemia in type 2 diabetes may be due to continuous decline in insulin secretion secondary to β-cell dysfunction and decreased insulin sensitivity. The purpose of this prospective cohort study was to evaluate whether early insulin therapy is more advantageous in achieving long-term optimal glycemic control with improved B cell function than oral drugs in the recently diagnosed type 2 diabetes mellitus.Methods: Sixty conse...

Introduction: Paragangliomas are rare endocrine tumors that represent extra-adrenal localization of pheochromocytomas. Signs of catecholamine excess are the most found manifestation of this tumor especialy hypertension. However, paragangliomas can be asymptomatic or can manifest with nonspecific signs. The association between pheochromocytomas and inflammatory diseases is exceptional.Observation: Here we report the case of a 26 years old male that was ad...

Introduction: Pheochromocytoma is a rare tumor of adrenal gland tissue that is responsible for secondary hypertension and other clinical manifestations resulting from catecholamine excess and it can result in severe damage to other body systems, especially the cardiovascular system. Here we report an atypical presentation of pheochromocytoma.Presentation: A 40 years old female patient that was admitted into the internal medicine ward with acute ischemia ...

Introduction: Hyperparathyroidism is defined by excessive secretion of parathyroid hormone (PTH) that is responsible for calcium regulation. Hyperparathyroidism can be primary in which the gland is affected and it produces PTH excessively or secondary or tertiary that cause hypersecretion of PTH as a regulatory response. The aim of our study was to describe patients with hyperparathyroidise diagnosed in internal medicine departement.Methods: It was a ret...

Introduction: Graves’ disease is an autoimmune disease that affects the thyroid gland and leads to a state of hyperthyroidism. This disease is caused by the production of antibodies that bind to and activate the thyroid-stimulating hormone (TSH) receptor. In some cases, Grave’ disease may be associated with other organ-specific or systemic autoimmune disorders. One of the most frequent multisystemic autoimmune disorders is Systemic lupus erythematosus (SLE). Many s...

Introduction: Apart from pulmonary and bone localizations, distant metastases from well differentiated thyroid carcinomas are very rare. Among them the adrenal ones are exceptional, and have generally a poor prognosis. The proof of the thyroid origin is not easy except if there is a histological confirmation by a CT guided biopsy of the adrenal tumor as in this observationObservation: A woman aged 56 was referred to our unit for pulmonary metastases of a...

Background: Mortality and morbidity after acute myocardial infarction (AMI) remain high even when myocardial reperfusion is successful. Thus, additional approaches are warranted. Erythropoietin (EPO) was found to be a cytoprotective molecule that might represent a novel strategy to limit the infarct size.Aim of the work: To investigate serum erythropoietin level and its relation to infarct size in Egyptian patients with AMI.Methods...

Objectives: The long-term outcome of bariatric surgery on renal function in the morbidly obese renal transplant recipient is still unknown. We describe three cases of morbidly obese renal transplant recipients who have subsequently undergone bariatric surgery.Patient 1: A 44-year-old man (BMI 42.2 kg/m2) had received a renal transplant for chronic renal disease secondary to childhood reflux nephropathy. Laparoscopic Roux-en-Y gastric bypass re...